BDBM50343352 2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one::4-(4-hydroxy-2-oxo-2H-3-chromenyl)-4-phenyl-2-butanone::4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one::4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one::CHEMBL1464::Coumadin::Jantoven::Warfarin4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one::wafarin::warfarin::warfarine

SMILES CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

InChI Key InChIKey=PJVWKTKQMONHTI-UHFFFAOYSA-N

Data  6 KI  3 IC50  10 Kd

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343352   

TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Rattus norvegicus (Rat))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  3.26E+4nM ΔG°:  -6.36kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  5.20E+4nM ΔG°:  -6.08kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed